Message type: E = Error
Message class:  COM_SE_SEARCH - SES: End user messages -> Translate to maximum languages 
Message number: 003
Message text: RFC destination in table COM_SE_SEARCH is not defined
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The SAP error message COM_SE_SEARCH003 indicates that there is an issue with the RFC (Remote Function Call) destination related to the COM_SE_SEARCH table. Specifically, it means that the RFC destination required for the search functionality is not defined in the system.
Cause: Missing RFC Destination: The primary cause of this error is that the RFC destination required for the COM_SE_SEARCH functionality is not defined in the SAP system.
Configuration Issues: There may be configuration issues in the system that prevent the RFC destination from being recognized or properly set up. Transport Issues: If the system has recently undergone a transport, the necessary configurations may not have been transported correctly. Authorization Issues: The user may not have the necessary authorizations to access the RFC destination.
Solution: Define the RFC Destination: Go to transaction SM59 (RFC Destinations). Check if the required RFC destination is defined. If it is missing, create a new RFC destination with the appropriate settings. Ensure that the destination
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