How To Fix SY443 - The specified instance is not active

SAP Error Message - Details

• Message type: E = Error

• Message class: SY - ABAP/4 system messages

• Message number: 443

• Message text: The specified instance is not active

What causes this issue?

The object display in the debugger contains an object reference.
However, the garbage collector has recognized the object as garbage and
"collected" it. This means that the object reference is no longer
valid.
Background Information:
ABAP Objects has its own automatic memory management for objects. When
an object is no longer accessible using any object- or interface
references, the memory management ("garbage collector") releases the
memory space that the object had been occupying. This space can then be
reused by a later CREATE OBJECT statement.

The system issues an error message and will not allow you to continue with this transaction until the error is resolved.

System Response

How to fix this error?

Enter a valid object index. All object references shown in the Debugger
are valid. It is better to navigate to the object display by
double-clicking on the reference value than to enter the object index
directly.

Error message extract from SAP system. Copyright SAP SE.