Message type: E = Error
Message class:  CNVMBTRFC - Messages used in RFC Management and its objects 
Message number: 121
Message text: Set destination state failed
Since SAP believes that this specific error message is 'self-explanatory,' no more information has been given.The majority of messages in the SAP system have a message text, however this is frequently insufficient to comprehend or resolve the problem.
To make things easier, more detailed information is frequently added to describe the issue, how to fix it, and the necessary steps or configuration modifications.
Unfortunately, there isn't any extra information in this error notice.
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The SAP error message CNVMBTRFC121: Set destination state failed typically occurs in the context of data migration or during the execution of a remote function call (RFC) in SAP systems. This error can arise due to various reasons, and understanding the cause is crucial for finding an appropriate solution. Possible Causes: Network Issues: There may be network connectivity problems between the SAP systems involved in the RFC call. Configuration Errors: Incorrect configuration of the RFC destination in transaction SM59 can lead to this error. Authorization Issues: The user executing the RFC may not have the necessary authorizations to perform the operation. System Load: High system load or performance issues can cause timeouts or failures in setting the destination state. Transport Layer Issues: Problems with the transport layer or middleware can also lead to this error. SAP Notes: There may be specific SAP Notes that address known issues related to this error. Solutions: Check Network Connectivity: Ensure that there are
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